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An aphthous ulcer, commonly known as a canker sore, is an open sore that is usually found in your mouth.

Some people develop them inside their lips or cheeks. There are more than 3 million cases per year in the US alone.

People with Colitis, Crohn's or Celiac disease often develop canker sores more frequently than the general population.

Canker sores usually heal within one to three weeks without treatment, while the pain typically subsides in 7 to 10 days. Severe canker sores may take up to six weeks to heal.



Short on time? Watch this short video that summarizes of some of the key findings resulting from recent clinical trials.


Past and Present Treatments

Treatment options for canker sores have to date been limited to home remedies, gels, mouth washes and just waiting for them to heal. In severe cases, sometimes antibiotics such as Monodox, Adoxa, Vibramycin are prescribed.

Low Level Laser Therapy, or LLLT, has been proven through clinical studies to be a highly effective treatment which can both shorten healing time (by roughly half) and immediately reduce pain.

The problem is that using lasers is both cost and time prohibitive as they can cost thousands of dollars and must be operated by trained medical staff.

LLLT is conducted by applying specific wavelengths of light to canker sores with a specific energy output measured in milliwatts per centimeter squared (mW/cm2).

However, LED (light-emitting diode) technology has recently advanced to where LED’s are now able to produce the same specifications of light as what was previously only possible with lasers.

Luminance Medical has leveraged this LED technology to create the Luminance RED.

An examination of clinical studies allows us to better understand how the treatment works.



Clinical evaluation of low-level laser treatment for recurring aphthous stomatitis

Authors: De Souza TO, Martins MA, Bussadori SK, Fernandes KP, Tanji EY, Mesquita-Ferrari RA, Martins MD.

Link to Study: https://www.ncbi.nlm.nih.gov/pubmed/20950190

Summary: One placebo-controlled study recently concluded that when red light was applied to canker sores it reduces the average healing time from 8.9 days (control group) to 3.1 days (treatment group).

 On a day by day basis, the group that received the red-light treatment saw a dramatic reduction in the size of the sore when compared to the group that received no treatment.



Assessment of immediate pain relief with laser treatment in recurrent aphthous stomatitis

Authors: Prasad R S, Pai A.

Link to Study: https://www.ncbi.nlm.nih.gov/pubmed/23622766

Summary: This study examined how applying LLLT impacted the levels of pain in patients with canker sores. The group that received treatment immediately experienced a 92% reduction in pain versus a 1% reduction in the placebo group.

 This study also found a nearly 50% reduction in healing time between the two groups with an average time to complete healing in the treatment group of 4.08 days, and in the group not receiving treatment of 7.84 days.



Clinical assessment of the therapeutic effect of low-level laser therapy on chronic recurrent aphthous stomatitis

Authors: Hristina Lalabonova and Hristo Daskalov

Link To Study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC

Summary: An important step in the healing process is called Epithelialization, which refers to when the initial healing barrier of cells is formed over the sore.

In this 3rd study researchers found that when red light was applied to canker sores, it reduced the time necessary to reach this important step in the healing process.

24 hours after the treatment, 77% of patients who received treatment had reached Epithelialization, where none of the non-treated group had.



As you can see from this data, when you are able to treat a canker sore with red light, you will reduce pain and heal faster.

However, the light must be applied at both the proper wavelength and irradiance (or power) to achieve these results.

The Luminance RED was designed specifically to meet these specifications and boasts a 100mW/cm2 irradiance output and produces a 637.5 nanometer red light wavelength.